PICKEM
PICK'EM POOL · WEEK 10
NFL PICK'EM PICKS WEEK 10 2026
The model’s straight-up pick for every Week 10game, ordered most confident to least, for pick’em pools. Our win probability, not a bet.
81%
TOP PICK · BUF
65.7%
OUR 2026 SU ACCURACY
6
FAVORED 70%+ THIS WEEK
Updated · Week 10 2026 picks
THE SHORT ANSWER
Our most confident Week 10 pick'em pick is the Buffalo Bills over the New York Jets, straight up at 81% win probability.
The next-safest picks are the Jacksonville Jaguars at 79% and the Los Angeles Rams at 76%.
No game this week is a coin flip; every pick clears 55% win probability.
6 of this week's 14 games are 70% or better favorites, straight up.
EVERY WEEK 10 GAME, MOST CONFIDENT FIRST
Ranked by the model’s win probability for the picked side, straight up. Where a market spread is posted, we note our pick’s number against it, informational only.
| # | Pick | Opponent | Win % | |
|---|---|---|---|---|
| 1 |  Buffalo Bills | at NYJ Against the spread, our pick is Buffalo Bills -7.5. | 81% | STRONG |
| 2 |  Jacksonville Jaguars | at TEN Against the spread, our pick is Jacksonville Jaguars -10.0. | 79% | STRONG |
| 3 |  Los Angeles Rams | at ARI Against the spread, our pick is Los Angeles Rams -7.0. | 76% | STRONG |
| 4 |  Seattle Seahawks | at LV Against the spread, our pick is Seattle Seahawks -3.0. | 71% | STRONG |
| 5 |  San Francisco 49ers | at DAL Against the spread, our pick is San Francisco 49ers -4.5. | 71% | STRONG |
| 6 |  Baltimore Ravens | vs LAC Against the spread, our pick is Baltimore Ravens -5.5. | 70% | STRONG |
| 7 |  New York Giants | vs WAS Against the spread, our pick is New York Giants -1.5. | 68% | SOLID |
| 8 |  Houston Texans | at CLE Against the spread, our pick is Houston Texans -4.5. | 67% | SOLID |
| 9 |  New Orleans Saints | vs CAR Against the spread, our pick is New Orleans Saints -1.5. | 65% | SOLID |
| 10 |  Detroit Lions | vs NE Against the spread, our pick is Detroit Lions -3.0. | 65% | SOLID |
| 11 |  Indianapolis Colts | vs MIA Against the spread, our pick is Indianapolis Colts -2.5. | 62% | SOLID |
| 12 |  Green Bay Packers | vs MIN Against the spread, our pick is Green Bay Packers -3.5. | 61% | SOLID |
| 13 |  Pittsburgh Steelers | at CIN Against the spread, our pick is Pittsburgh Steelers +3.5. | 61% | SOLID |
| 14 |  Kansas City Chiefs | at ATL Against the spread, our pick is Kansas City Chiefs -3.5. | 60% | SOLID |
Before kickoff
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HOW TO WIN YOUR PICK’EM POOL
Straight up, not against the spread
A pick’em pool only cares who wins the game, not by how much, so the right number to rank by is straight-up win probability, which is exactly what the board above does. A team can be a big underdog against the spread and still be the safer straight-up pick.
The favorite isn’t always obvious
Public perception and the betting line both lean toward name-brand teams and recent results. Our model weighs six seasons of play-by-play efficiency instead, which is why our straight-up rankings sometimes differ from the spread favorite, especially on divisional and rivalry games where the public overrates a familiar matchup.
Coin flips decide most pools
Most weeks come down to how you handle the games near 50%, not the easy calls. Treat a coin-flip game as a genuine 50/50 and pick a side you can defend, rather than assuming the model (or anyone else) has a real edge on it.
QUESTIONS
Our most confident Week 10 pick'em pick is the Buffalo Bills straight up over the New York Jets, at 81% win probability. Every game on the slate is ranked the same way below.
Each week you pick every game straight up (no point spread), just who you think wins. Most pools score one point per correct pick and tally the season; some weight picks by confidence, which is what our confidence pool page does separately.
A standard pick'em pool only cares who wins, not by how much, so straight-up win probability (what this page ranks by) is the right number to use. We also show the market spread when one is posted so you can see where the market's margin sits, but that number is informational, not a covering prediction.
NoPunt's straight-up pick accuracy is 66.4% across six seasons, every pick graded in public. These pick'em rankings use the same model's win probability for each game. Past results are not a guarantee.
Playing a confidence pool instead? See our confidence pool picks, with points assigned and expected points shown.
CONFIDENCE POOL PICKS →Picks are the model’s own, straight up. Past results. Not financial advice.