PICKEM
PICK'EM POOL · WEEK 6
NFL PICK'EM PICKS WEEK 6 2026
The model’s straight-up pick for every Week 6game, ordered most confident to least, for pick’em pools. Our win probability, not a bet.
83%
TOP PICK · SF
65.7%
OUR 2026 SU ACCURACY
7
FAVORED 70%+ THIS WEEK
Updated · Week 6 2026 picks
THE SHORT ANSWER
Our most confident Week 6 pick'em pick is the San Francisco 49ers over the Washington Commanders, straight up at 83% win probability.
The next-safest picks are the Los Angeles Rams at 81% and the New England Patriots at 81%.
No game this week is a coin flip; every pick clears 55% win probability.
7 of this week's 14 games are 70% or better favorites, straight up.
The Week 6 top pick'em pick hit: the San Francisco 49ers beat the Washington Commanders 23-17.
EVERY WEEK 6 GAME, MOST CONFIDENT FIRST
Ranked by the model’s win probability for the picked side, straight up. Where a market spread is posted, we note our pick’s number against it, informational only.
| # | Pick | Opponent | Win % | |
|---|---|---|---|---|
| 1 |  San Francisco 49ers | vs WAS Against the spread, our pick is San Francisco 49ers -7.5. | 83% | STRONG |
| 2 |  Los Angeles Rams | vs ARI Against the spread, our pick is Los Angeles Rams -12.5. | 81% | STRONG |
| 3 |  New England Patriots | vs NYJ Against the spread, our pick is New England Patriots -7.5. | 81% | STRONG |
| 4 |  Buffalo Bills | at LV Against the spread, our pick is Buffalo Bills -5.5. | 75% | STRONG |
| 5 |  Kansas City Chiefs | vs LAC Against the spread, our pick is Kansas City Chiefs -7.5. | 75% | STRONG |
| 6 |  Jacksonville Jaguars | vs HOU Against the spread, our pick is Jacksonville Jaguars -2.5. | 73% | STRONG |
| 7 |  Indianapolis Colts | vs TEN Against the spread, our pick is Indianapolis Colts -7.0. | 73% | STRONG |
| 8 |  Baltimore Ravens | at CLE Against the spread, our pick is Baltimore Ravens -3.0. | 69% | SOLID |
| 9 |  Green Bay Packers | vs DAL Against the spread, our pick is Green Bay Packers -1.5. | 64% | SOLID |
| 10 |  New York Giants | vs NO Against the spread, our pick is New York Giants +1.5. | 64% | SOLID |
| 11 |  Pittsburgh Steelers | at TB Against the spread, our pick is Pittsburgh Steelers -2.5. | 64% | SOLID |
| 12 |  Denver Broncos | vs SEA Against the spread, our pick is Denver Broncos +2.5. | 64% | SOLID |
| 13 |  Atlanta Falcons | vs CHI Against the spread, our pick is Atlanta Falcons +1.5. | 60% | SOLID |
| 14 |  Philadelphia Eagles | vs CAR Against the spread, our pick is Philadelphia Eagles +3.0. | 58% | SOLID |
Before kickoff
Get the pick'em picks every week, free
Every game ranked by win probability, straight up, in your inbox before the slate locks. Free, every week of the season.
HOW TO WIN YOUR PICK’EM POOL
Straight up, not against the spread
A pick’em pool only cares who wins the game, not by how much, so the right number to rank by is straight-up win probability, which is exactly what the board above does. A team can be a big underdog against the spread and still be the safer straight-up pick.
The favorite isn’t always obvious
Public perception and the betting line both lean toward name-brand teams and recent results. Our model weighs six seasons of play-by-play efficiency instead, which is why our straight-up rankings sometimes differ from the spread favorite, especially on divisional and rivalry games where the public overrates a familiar matchup.
Coin flips decide most pools
Most weeks come down to how you handle the games near 50%, not the easy calls. Treat a coin-flip game as a genuine 50/50 and pick a side you can defend, rather than assuming the model (or anyone else) has a real edge on it.
QUESTIONS
Our most confident Week 6 pick'em pick is the San Francisco 49ers straight up over the Washington Commanders, at 83% win probability. Every game on the slate is ranked the same way below.
Each week you pick every game straight up (no point spread), just who you think wins. Most pools score one point per correct pick and tally the season; some weight picks by confidence, which is what our confidence pool page does separately.
A standard pick'em pool only cares who wins, not by how much, so straight-up win probability (what this page ranks by) is the right number to use. We also show the market spread when one is posted so you can see where the market's margin sits, but that number is informational, not a covering prediction.
NoPunt's straight-up pick accuracy is 66.4% across six seasons, every pick graded in public. These pick'em rankings use the same model's win probability for each game. Past results are not a guarantee.
Playing a confidence pool instead? See our confidence pool picks, with points assigned and expected points shown.
CONFIDENCE POOL PICKS →Picks are the model’s own, straight up. Past results. Not financial advice.